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Recent Publications

1. Abe, Y; Muto, M; Nieda, M; Nakagawa, Y; Nicol, A; Kaneko, T; Goto, S; Yokogawa, K; and Suzuki, K. (2009) Clinical and immunological evaluation of zolendronate-activated Vgamma9Vdelta2 T cell-based immunotherapy for patients with multiple myeloma. Experimental Hematology 37(8):956-968
2. Tokuyama, H; Hagi, T; Mattarollo, SR; Morley, J; Wang, Q; Fai-So, H; Moriyasu, F; Nieda, M; and Nicol, AJ. (2008) Vgamma9Vdelta2 T cell cytotoxicity against tumor cells is enhanced by monoclonal antibody drugs-Rituximab and trastuzumab. International Journal of Cancer 122(11), 2526-34
3. Takahara, M; Miyai, M; Tomiyama, M; Mutou, M; Nicol, AJ; Nieda, M. (2008) Co-pulsing tumor antigen pulsed dendrictic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vy9yo T cell activation. Journal of Leukocyte Biology 83(3):742-54.
4. Mattarollo, S; Kenna, T; Nieda, M; Nicol AJ. (2007) Chemotherapy and Zoledronate sensitize solid tumor cells to V?9Vd2 T cell cytotoxicity. Cancer Immunology and Immunotherapy 56(8):1285-97
5. Lickliter, JD; Cox, J; Lin, H; Nieda, M and Nicol, AJ (2007) Small-molecule Bcl-2 inhibitors sensitize tumour cells to immune-mediated destruction. British Journal of Cancer 96(4):600-8.
6. Mattarollo, SR; Kenna, T; Nieda, M and Nicol, AJ (2006) “Chemotherapy pre-treatment sensitizes solid tumor-derived targets to Va24+NKT cell-mediated cytotoxicity” International Journal of Cancer 119(7):1630-7
7. Lin, H; Nieda M; Hutton JF; Rozenkov V and Nicol, AJ (2006) “Analysis of the effect of different NKT cell subpopulations on the activation of CD4 and CD8 T cells, NK cells and B cells” Experimental Hematology 34(3): 289-295.
8. Lin, H; Nieda M; Hutton JF; Rozenkov V and Nicol, AJ (2006) “Comparative gene expression analysis of NKT cell subpopulations” Journal of Leukocyte Biology 80(1):164-73.
9. Crough, T; Purdie, DM; Okai, M; Maksoud, A; Nieda, M; and Nicol, AJ (2004) Modulation of human Ca24+Vb11: NKT cells by age, malignancy and conventional anti-cancer therapies. British Journal of Cancer 91(11):1880-6.
10. Crough, T; Nieda, M; Nicol, AJ (2004) Granulocyte Colony-Stimulation Factor Suppresses a-Galactosyl Ceramide Responsive Human Ca24+Vb11+ NIKT Cells and Causes Th2 Polarization. Journal of Immunology 173(8):4960-6.
11. Lin, H; Nieda, M; Nicol, AJ (2004) Differential proliferative response of NKT Cell subpopulations to in-vitro stimulation in the presence of different cytokines. European Journal of Immunology. 34(10):2664-71.
12. Nieda, M; Okai, M; Tazbirkova, A; Lin, H; Yamaura, A; Ide, K; Abraham, R; Juji, T; Macfarlane, D; and Nicol, AJ (2004) Therapeutic activation of Va24+Vß11+NKT cells in human subjects results in highly co-ordinated secondary activation of acquired and innate immunity. Blood 103(2):383-389.
13. Tazbirkova, A; Maksoud, A; Horley, D; Okai, M; Crough, T; Nicol AJ; (2003) Effects of leukapheresis protocol, cell processing and cryopreservation on the generation of monocyte-derived dendritic cells for immune therapy Cytotherapy 5 (1): 31-39
14. Kashiwase, K; Kikuchi, A; Ando, Y; Nicol, AJ; Porcelli, SA; Tokunaga, K; Omine, M; Satake, M; Juji, T; Nieda, M; and Yasuhiko Koezuka (2003). The CD1d natural killer T-cell antigen presentation pathway is highly conserved between humans and rhesus macaques. Immunogenetics. 54:776-781
15. Henderson, RD; Rajah, T; Nicol, AJ; Read, SJ (2003) Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm. Neurology. 60(2):326-8
16. Clark, T; Nieda, M; Morton, AJ; Boyd, A; Bashford, J; Durrant, S; Nicol, AJ.(2002) Donor derived b2a2-specific T cells for immunotherapy of CML Journal of Immunotherapy 25(6):469-75
17. Okai, M; Nieda, M; Tazbirkova, A; Horley, D; Kikuchi, A; Durrant, S; Takahashi, T; Abraham, R; Yagita, H; Juji,T; Nicol, AJ.(2002) Human peripheral blood Va24+Vß11+NKT cells expand following administration of a-Galactosylceramide-pulsed dendritic cells Vox sanguis 83(3):250-3.
18. Lapteva, N; Nieda, M; Ando, Y; Nicol AJ; Ide, K; Hatta-Ohashe, Y; Egawa, K, Juji, T; Tokunaga, K. (2001) Gene Expression Profiling in Human Monocytes, Monocyte-derived Dendritic cells and ?-galactosylceramide-pulsed Monocyte-derived Dendritic cells Biochemical and Biophysical Research Communications ;289(2):531-8
19. Kikuchi, A., Nieda M., Schmidt C., Koezuka, Y., Ishihara, S., Ishikawa, Y., Tadokoro, K., Durrant, S., Boyd, A., Juji, T., Nicol, A. (2001) In vitro anti-tumour activity of a-Galactosyl Ceramide stimulated human invariant V?24NKT cells against melanoma British Journal of Cancer Sep 1;85(5):741-6.
20. Nieda, M., Nicol, AJ., Koezuka, Y., Kikuchi, A., Lapteva, N.,Tanaka, Y., Tokunaga, K., Suzuki, K., Kayagaki, N., Yagiat, H., Hirai, H. & Juji, T. (2001) TRAIL expression by activated human CD4+ V-alpha 24+NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukaemia cells. Blood 97 2067-74
21. Nieda, M., Kikuchi, A., Nicol, A., Koezuka, Y., Ando, Y., Ishihara, S., Lapteva, N., Yabe, T., Tokunaga, K., Tadokoro K., & Juji T. (2001) Dendritic cells rapidly undergo apoptosis in vitro following culture with activated CD4+Va24 natural killer T cells expressing CD40L Immunology 102 1-14
22. Nicol, A., Nieda, M., Koezuka, Y., Porcelli, S., Suzuki, K., Tadokoro, K., Durrant, S. & Juji, T. (2000) Dendritic cells are targets for human invariant V?24+ NKT cell cytototoxic activity - an important immune regulatory function. Experimental Hematology 28(3) 276-82
23. Takahashi, T., Nieda, M., Koezuka, Y., Nicol, A. J., Porcelli, S., Ishikawa, Y., Tadokoro, K., Hirai, H. & Juji, T. (2000) Analysis of human V?24+ NKT cells activated by ?-glycolsylceramide-pulsed monocyte derived dendritic cells. Journal of Immunology 164, 4458-4464
24. Nicol, A. J., Nieda, M., Koezuka, Y., Porcelli, S., Suzuki, K., Tadokoro, K., Durrant, S. & Juji, T. (2000) Human invariant V?24+ NKT cells activated by ?-GalactosylCeramide(KRN7000) have cytotoxic antitumour activity through mechanisms distinct from T cells and NK cells. Immunology, 99, 229
25. Nieda, M., Nicol, A., Koezuka, Y., Kikuchi, A., Takahashi, T., Nakamura, H., Furukawa, H., Yabe, T., Ishikawa, Y., Tadokoro, K. & Juji, T. (1999) Activation of human V?24NKT cells by ?-glycosylceramide in a CD1d-restricted and V?24TCR-mediated manner. Human Immunology, 60, 10-19.
26. Denning-Kendall, P A., Nicol, A. J., Horsley, H., Donaldson, C., Bradley, B. & Hows, J. M. (1998) Is in vitro expansion of human cord blood cells clinically relevant? Bone Marrow Transplantation, 21, 225-232.
27. Denning-Kendall, P.A., Horsley, H., Nicol, A., Nieda, M., Bradley, B. & Hows, J. M. (1998) Clinical application of in vitro expansion of cord blood. Bone Marrow Transplantation, 22, S63-S65.
28. Nieda, M., Nicol, A., Kikuchi, A., Kashiwase, K., Taylor, K., Suzuki, K., Tadokoro, K. & Juji, T. (1998) Dendritic cells stimulate the expansion of bcr-abl specific CD8+ T cells with cytotoxic activity against leukemic cells from patients with chronic myeloid leukemia. Blood, 91, 977-983.
29. Denning-Kendall, P., Donaldson, C., Nicol, A. J., Bradley, B. A. & Hows, J. M. (1996) Optimization of red cell depletion of cord blood for banking. Experimental Hematology, 24, 1394-1401.
30. Donaldson, C., Armitage, W. J., Denning-Kendall, P. A., Nicol, A. J., Bradley, B. A. & Hows, J. M. (1996) Optimal cryopreservation of human umbilical cord blood (UCB). Bone Marrow Transplantation, 18, 725-731.
31. Hows, J., Nicol, A., Denning-Kendall, P., Donaldson, C., Nieda, M. & Bradley, B. (1996) Cord Blood as an alternate source of haemopoietic stem cells. Annals of Oncology, 7, 47-51.
32. Nieda, M., Nicol, A. J., Denning-Kendall, P. A., Sweetenham, J., Bradley, B. & Hows, J. M. (1996) Endothelial cells derived from CD34+ human umbilical cord blood cells support hematopoiesis. British Journal of Haematology, 98, 775-777.
33. Nicol, A. J., Nieda, M., Donaldson, C., Denning-Kendall, P. A., Bradley, B. & Hows, J. (1995) Analysis of cord blood CD34+ cells purified after cryopreservation. Experimental Hematology, 23, 1589-1594.
34. Donaldson, C., Denning-Kendall, P., Nicol, A. J., Laundy, G., Hows, J. & Bradley, B. (1994) Human Cord Blood Banking: An Alternative to Unrelated Marrow Donor Registries? European Foundation for Immunogenetics Newsletter, 20-21.