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Current Research Projects
Liver
Fibrogenesis:
We
currently have several projects underway examining mechanisms and
treatments of hepatic fibrosis. These include:
- Post-liver
transplantation disease recurrence and the influence of immunosuppression
in this process.
- The
antifibrogenic potential of sirolimus and everolimus in cholestatic
liver disease.
- Epithelial
to meshenchymal transition and the ductular reaction as pathways
to fibrosis in cholestatic liver disease.
Co-Toxic
Liver Disease:
Research
projects in co-toxic liver disease include:
- The
role of hepcidin and iron transporters in disease progression
in alcohol and iron co-toxic liver disease.
- The
role of hypoxia and proteosome function leading to liver injury
in alcoholic liver disease in the setting of iron-overload.
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