Research: Centre for Immune and Targeted Therapy

Our publications

Book Chapter

Book Titled “Natural Killer T cells: Balancing the Regulation of Tumor Immunity”

Chapter Title  “Clinical Trials using NKT cell activation for advanced malignant disease”

Authors Nicol AJ, Nieda M. (in preparation)

Refereed Articles published in International Journals (2008-2010)

1. Nicol AJ, Hagi T, Nieda M (2011) Addition of α-Galactosylceramide to tumour pulsed dendritic cell vaccines enhances tumour antigen specific T cell responses and leads to clinical responses in patients with metastatic melanoma Journal of Clinical Oncology (submitted) (A ranked journal)

2. Nicol AJ, Tokuyama H, Mattarollo SR, Hagi T, Suzuki K, Yokokawa K, Nieda M (2010) Clinical evaluation of autologous gamma deltas T cell-based immunotherapy for metastatic solid tumours. British Journal of Cancer (submitted) (A ranked journal)

3. Nicol AJ, Tazbirkova A, Nieda M (2010) Comparison of clinical and immunological effects of intravenous and intradermal administration of α-GalactosylCeramide (KRN7000) – pulsed dendritic cells. Clinical Cancer Research (submitted) (A ranked journal)

4. Abe Y, Muto M, Nieda M, Nakagawa Y,  Nicol A, Kaneko T, Goto S, Yokogawa K and Suzuki K. (2009) ‘Clinical and immunological evaluation of zolendronate-activated Vgamma9Vdelta2 T cell-based immunotherapy for patients with multiple myeloma’, Experimental Hematology 37(8):956-968. ( A ranked journal, citations 10)

5. Tokuyama H, Hagi T, Mattarollo SR, Morley J, Wang Q, Fai-So H, Moriyasu F, Nieda M & Nicol AJ. (2008), ‘Vgamma9Vdelta2 T cell cytotoxicity against tumor cells is enhanced by monoclonal antibody drugs-Rituximab and trastuzumab’, International Journal of Cancer 122(11), 2526-34. (A ranked journal, citations 14)

6. Takahara M, Miyai M, Tomiyama M, Mutou M, Nicol AJ, Nieda M. (2008) Co-pulsing tumor antigen pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vγ9γδ T cell activation. Journal of Leukocyte Biology 83(3):742-54. (A ranked journal, citations 4)